Article-Journal

Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns
High-throughput sequencing of 16S ribosomal RNA gene amplicons has facilitated understanding of complex microbial communities, but the …
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Normalization and Microbial Differential Abundance Strategies Depend upon Data Characteristics
Background Data from 16S ribosomal RNA (rRNA) amplicon sequencing present challenges to ecological and statistical interpretation. In …
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Lifestyle Chemistries from Phones for Individual Profiling
Imagine a scenario where personal belongings such as pens, keys, phones, or handbags are found at an investigative site. It is often …
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Correlation Detection Strategies in Microbial Data Sets Vary Widely in Sensitivity and Precision
Disruption of healthy microbial communities has been linked to numerous diseases, yet microbial interactions are little understood. …
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Microbiome-Wide Association Studies Link Dynamic Microbial Consortia to Disease
Rapid advances in DNA sequencing, metabolomics, proteomics and computational tools are dramatically increasing access to the microbiome …
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Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies
Immediate freezing at −20°C or below has been considered the gold standard for microbiome preservation, yet this approach is not …
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Open-Source Sequence Clustering Methods Improve the State Of the Art
Sequence clustering is a common early step in amplicon-based microbial community analysis, when raw sequencing reads are clustered into …
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Microbial Community Assembly and Metabolic Function during Mammalian Corpse Decomposition
Decomposition spawns a microbial zoo The death of a large animal represents a food bonanza for microorganisms. Metcalf et al. monitored …
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Tiny Microbes, Enormous Impacts: What Matters in Gut Microbiome Studies?
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Turning Participatory Microbiome Research into Usable Data: Lessons from the American Gut Project
The role of the human microbiome is the subject of continued investigation resulting in increased understanding. However, current …
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